Table 1 Patient characteristics
From: Electrophysiological differences of randomized deep sedation with dexmedetomidine versus propofol
All N = 160 | DEX group N = 80 | PRO group N = 80 | P value | |
|---|---|---|---|---|
Age, years | 65 ± 11 | 66 ± 10 | 64 ± 12 | 0.446 |
Gender, female | 51 (32%) | 28 (35%) | 23 (29%) | 0.396 |
Body mass index, kg/m2 | 27 ± 4 | 26 ± 4 | 27 ± 4 | 0.074 |
Arterial hypertension | 86 (54%) | 44 (55%) | 42 (53%) | 0.751 |
Diabetes mellitus | 12 (8%) | 5 (6%) | 7 (9%) | 0.548 |
Coronary artery disease | 16 (10%) | 10 (13%) | 6 (8%) | 0.292 |
History of stroke/embolism | 14 (9%) | 7 (9%) | 7 (9%) | 1.000 |
Peripheral artery disease | 14 (9%) | 6 (8%) | 8 (10%) | 0.576 |
History of congestive heart failure | 19 (12%) | 12 (15%) | 7 (9%) | 0.222 |
CHA2DS2Vasc score | 2 (1; 3) | 2 (1; 3) | 2 (1; 3) | 0.608 |
Obstructive sleep apnea | 14 (9%) | 6 (8%) | 8 (10%) | 0.576 |
Pacemaker or ICD | 5 (3%) | 4 (5%) | 1 (1%) | 0.173 |
Paroxysmal atrial fibrillation | 115 (72%) | 59 (74%) | 56 (70%) | 0.598 |
Previous cardioversion | 51 (32%) | 27 (34%) | 24 (30%) | 0.611 |
LVEF, % | 58 ± 8 | 57 ± 9 | 59 ± 7 | 0.140 |
LAVI ml/m2 | 38 ± 13 | 40 ± 14 | 36 ± 12 | 0.083 |
Drugs | ||||
Betablocker | 99 (63%) | 47 (59%) | 52 (67%) | 0.304 |
Calcium channel blocker | 1 (1%) | 1 (1%) | - | 1.000 |
Digoxin | 1 (1%) | 1 (1%) | - | 1.000 |
Flecainid/propafenon | 25 (16%) | 11 (14%) | 14 (18%) | 0.470 |
Amiodarone | 2 (1%) | - | 2 (3%) | 0.242 |
Sotalol | 7 (4%) | 5 (6%) | 2 (3%) | 0.443 |
ECG | ||||
RR interval, msa | 178 ± 37 | 184 ± 41 | 171 ± 31 | 0.060 |
PR, ms* | 1014 ± 208 | 1011 ± 231 | 1017 ± 181 | 0.875 |
QRS, ms | 100 ± 16 | 102 ± 18 | 99 ± 14 | 0.252 |
QT, ms | 418 ± 51 | 423 ± 54 | 413 ± 47 | 0.223 |
QTc (Bazett formula), ms | 437 ± 29 | 442 ± 29 | 432 ± 28 | 0.042 |