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Table 1 Patient characteristics

From: Electrophysiological differences of randomized deep sedation with dexmedetomidine versus propofol

 

All

N = 160

DEX group

N = 80

PRO group

N = 80

P value

Age, years

65 ± 11

66 ± 10

64 ± 12

0.446

Gender, female

51 (32%)

28 (35%)

23 (29%)

0.396

Body mass index, kg/m2

27 ± 4

26 ± 4

27 ± 4

0.074

Arterial hypertension

86 (54%)

44 (55%)

42 (53%)

0.751

Diabetes mellitus

12 (8%)

5 (6%)

7 (9%)

0.548

Coronary artery disease

16 (10%)

10 (13%)

6 (8%)

0.292

History of stroke/embolism

14 (9%)

7 (9%)

7 (9%)

1.000

Peripheral artery disease

14 (9%)

6 (8%)

8 (10%)

0.576

History of congestive heart failure

19 (12%)

12 (15%)

7 (9%)

0.222

CHA2DS2Vasc score

2 (1; 3)

2 (1; 3)

2 (1; 3)

0.608

Obstructive sleep apnea

14 (9%)

6 (8%)

8 (10%)

0.576

Pacemaker or ICD

5 (3%)

4 (5%)

1 (1%)

0.173

Paroxysmal atrial fibrillation

115 (72%)

59 (74%)

56 (70%)

0.598

Previous cardioversion

51 (32%)

27 (34%)

24 (30%)

0.611

LVEF, %

58 ± 8

57 ± 9

59 ± 7

0.140

LAVI ml/m2

38 ± 13

40 ± 14

36 ± 12

0.083

Drugs

 Betablocker

99 (63%)

47 (59%)

52 (67%)

0.304

 Calcium channel blocker

1 (1%)

1 (1%)

-

1.000

 Digoxin

1 (1%)

1 (1%)

-

1.000

 Flecainid/propafenon

25 (16%)

11 (14%)

14 (18%)

0.470

 Amiodarone

2 (1%)

-

2 (3%)

0.242

 Sotalol

7 (4%)

5 (6%)

2 (3%)

0.443

ECG

 RR interval, msa

178 ± 37

184 ± 41

171 ± 31

0.060

 PR, ms*

1014 ± 208

1011 ± 231

1017 ± 181

0.875

 QRS, ms

100 ± 16

102 ± 18

99 ± 14

0.252

 QT, ms

418 ± 51

423 ± 54

413 ± 47

0.223

 QTc (Bazett formula), ms

437 ± 29

442 ± 29

432 ± 28

0.042

  1. BPM beats per minute, ICD internal cardioverter defibrillator, LAVI left atrial volume index, LVEF left ventricular ejection fraction
  2. Data are provided as mean ± standard deviation, as median with interquartile range (1st; 3rd) or frequencies with percentages
  3. aonly for patients in sinus rhythm